Science

Researchers at Kanazawa University report in Journal of Cell Science on a novel role of the small Ca2+-binding protein S100A11 in focal adhesion disassembly.

Researchers from Osaka University found that the oral bacterium Streptococcus gordonii activates another bacterial species, Fusobacterium nucleatum, to produce large quantities of methyl mercaptan, a compound responsible for bad breath. Disrupting this interaction could therefore help treat halitosis, and possibly also help prevent the development of more serious tooth and gum disease.

Researchers from Osaka University and collaborating partners succeeded in biomanufacturing from chemically synthesized sugar for the first time in the world. With refinement of this technology, one can envision a future society in which the sugar required for biomanufacturing can be obtained "anytime, anywhere, and at high rate". In the future, biomanufacturing using chemically synthesized sugar is expected to be a game changer in the biotechnology field—including the production of biochemicals, biofuels, and food, where sugar is an essential raw material—ultimately leading to the creation of a new bio-industry.

An innovative and more efficient way to produce fumaric acid that not only reduces carbon dioxide emissions, but also reuses waste resources to make biodegradable plastics

The properties of supramolecular polymers are dictated by the self-assembled state of the molecules. However, not much is known about the impact of morphologies on the properties of nano- and mesoscopic-scale polymeric assemblies. Recently, a research team demonstrated how terminus-free toroids and random coils derived from the same luminescent molecule show different photophysical properties. The team also presented a novel method for purifying the toroidal structure.

Researchers from the Institute of Industrial Science, The University of Tokyo have solved a foundational problem in transmitting quantum information, which could dramatically enhance the utility of integrated circuits and quantum computing.

AI records rare bird footage, Lighting up IoT and smart cities, Crystal language designs new materials, Detecting toxins with mobile phones, and Dragonfly wings for better aerodynamics. Plus join us for SciCom coffee. Read all in the latest Editor's Choice.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are growing placenta organoids, a 90-million-year old fossil, and how COVID-19 can cause insomnia, but people were more relaxed during the emergency measures.

Yokohama National University scientists are working towards creating a better tomorrow by addressing diverse challenges, from snow algae and tropical cyclones to AI cyberthreats, and much more.

The estate of the late Ms Diana Koh gifted S$1M to Duke-NUS Medical School and NUS Medicine to fund young cancer researchers and raise awareness about cancer research advances. The gift establishes research funds, grants, prizes, and learning series to support innovative approaches to cancer treatment by the next generation of scientists and clinicians.

A study led by Duke-NUS Medical School has found an important connection between cancer, stem cells and the building blocks of cholesterol. Specifically, the research reveals how the enzyme FAXDC2 influences cancer cell growth and differentiation through its role in cholesterol synthesis, suggesting possible new approaches to cancer treatment.

Theoretical predictions have been confirmed with the discovery of an outflow of molecular gas from a quasar when the Universe was less than a billion years old.

Researchers from Osaka University and IMRA AMERICA demonstrated a 300 GHz-band wireless link that was able to transmit data over a single channel at a rate of 240 gigabits per second. The wireless communication system employs signal generators based on lasers that have ultra-low phase noise in the sub-terahertz band. This rate is the highest so far reported at these frequencies and is a substantial step forward in 300 GHz-band communications for 6G networks.

Attended by President Ing-wen Tsai, Academia Sinica launched Taiwan's first self-developed 5-qubit superconducting full-stack quantum computer at its quantum computer progress presentation today. During the event, AS President James Liao presented the research team’s self-developed 4-inch quantum wafer to President Tsai. The event was also attended by Chia-Lung Lin, Secretary-­General to the President; Tsung-Tsong Wu, Chairman of the National Science and Technology Council and Chuan-Neng Lin, Vice Minister of Economic Affairs. It marks an important milestone in the development of Taiwan's quantum technology.

A team of researchers from Osaka Metropolitan University assessed the feasibility of conducting cardiopulmonary exercise testing with the upper limbs as an alternative to the conventional method that uses the lower limbs. The researchers investigated the relationship between heart rate and oxygen uptake during exercise stress tests using a cycle ergometer and an arm crank ergometer, and estimated maximal oxygen uptake. The study participants were 17 male collegiate athletes from rowing and cycling clubs. The results showed that the estimated maximal oxygen uptake for both rowing and cycling groups was lower on the arm crank ergometer than on the cycle ergometer. Additionally, this study showed that exercise testing using an upper extremity ergometer underestimates cardiopulmonary function, regardless of upper limb training status.

A theoretical framework for measuring the Reynolds similitude in superfluids could help demonstrate the existence of quantum viscosity

This week sees the launch of the first published content in Sustainable Microbiology, the new open access journal which will apply microbiology to sustainability. The journal is published by Applied Microbiology International.

Researchers from SANKEN (The Institute of Scientific and Industrial Research), at Osaka University developed an optical sensor consisting of carbon nanotube photodetectors and organic transistors formed on an ultrathin, flexible polymer film. A wireless system reads the images from the sensor. Experiments showed the sensor has high sensitivity, a wide bandwidth, and robustness to extreme deformation such as bending and crumpling. This sensor has high potential for use in applications such as non-destructive imaging, non-sampling liquid quality evaluation, wearable devices, and soft robotics.

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The Hayabusa2 mission that collected samples from the asteroid Ryugu has provided a treasure trove of insights into our solar system. After analyzing samples further, a team of researchers have unearthed evidence that cometary organic matter was transported from space to the near-Earth region.

Researchers from Thailand have pioneered the conversion of waste HDPE milk bottles into high-stiffness composites, utilizing PALF reinforcement for a 162% increase in flexural strength and 204% in modulus. This eco-friendly upcycling boosts mechanical properties while sequestering carbon, presenting a promising path for sustainable materials.

A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells.

Temperature-controlled, reversible shifting of molecular gear motion in a solid crystal opens new possibilities for material design.

Non-Heisenberg-type approximant crystals have many interesting properties and are intriguing for researchers of condensed matter physics. However, their magnetic phase diagrams, which are crucial for realizing their potential, remain completely unknown. Now, for the first time, a team of researchers has constructed the magnetic phase diagram of a non-Heisenberg Tsai-type 1/1 gold-gallium-terbium approximant crystal. This development marks a significant step forward for quasicrystal research and for the realization of magnetic refrigerators and spintronic devices.

A research group led by Osaka Metropolitan University has discovered significant nonreciprocal optical absorption of LiNiPO4, referred to as the optical diode effect, in which divalent nickel (Ni2+) ions are responsible for magnetism, by passing light at shortwave infrared wavelengths used in optical communications. Furthermore, they have uncovered that it is possible to switch the optical diode effect by applying a magnetic field. This is a step forward in the development of an innovative optical isolator that is more compact and can control light propagation, replacing the conventional optical isolators with complex structures

Researchers from Osaka University and collaborating partners have improved the efficiency of heat-to-electricity conversion in gallium arsenide semiconductor microstructures. By judicious spatial alignment of electrons within a two-dimensional electron gas system with multiple subbands, one can substantially enhance the power factor compared with previous iterations of analogous systems. This work is an important advance in modern thermoelectric technology and will benefit the global integration of the Internet of Things.

Researchers from Osaka University have discovered a novel treatment to relieve cytokine release syndrome (CRS), a life-threatening inflammation triggered by a serious infection or severe burn. Treatment with a short-acting antibody reduces the inflammatory effects of interleukin-6, a key cytokine in CRS while avoiding the side effects associated with previous longer-acting therapies.

Researchers from Osaka University have simplified the operation of an important class of chemical transformation: synthesis of beta-lactams, the intricate scaffold of many antibiotics. Their experimental protocol minimizes the toxicity that is a common feature of similar Fischer-carbene synthetic methodologies, and was used to synthesize the scaffold of the thienamycin antibiotic in high yield. This work is an important advancement in sustainable chemistry that should benefit drug development and other chemical syntheses.

Research by Assistant Professor Edison Ang Huixiang and his team from National Institute of Education/Nanyang Technological University Singapore

Unleashing stem cells from dog urine, Electronic Tongue, Tapping into human motion energy, How neurons network, and A radical use for plastic bags. Plus Communicating science two decades on. Read all in the latest Editor's Choice.